What is the difference between Antabuse and naltrexone?

Vivitrol (Naltrexone) is good for treating opioid and alcohol dependence. It needs to be used as directed and can’t be used with alcohol or opioid pain medications. Antabuse (disulfiram) is a first choice medicine for alcoholism.

Is Antabuse the same as naltrexone?

Are Antabuse and Vivitrol the Same Thing? Antabuse (disulfiram) and Vivitrol (naltrexone) are used to treat chronic alcoholism. Vivitrol is also used to prevent relapse to opioid dependence. Antabuse and Vivitrol belong to different drug classes.

Is disulfiram more effective than naltrexone?

Conclusions: Disulfiram is superior to naltrexone in preventing a relapse among alcohol-dependent men with family support. Comparison between these treatments in other settings and in different types of alcoholics is warranted.

Is there a substitute for Antabuse?

There are four FDA-approved medications for patients with alcohol use disorder: disulfiram (Antabuse), acamprosate (Campral), naltrexone (ReVia), and long-acting naltrexone (Vivitrol).

Can naltrexone be used with Antabuse?

Interactions between your drugs

Naltrexone may cause liver problems, and using it with other medications that can also affect the liver such as disulfiram may increase that risk.

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Is naltrexone bad for your liver?

Hepatotoxicity: Naltrexone has the capacity to cause hepatocellular injury when given in excessive doses. Naltrexone is contraindicated in acute hepatitis or liver failure, and its use in patients with active liver disease must be carefully considered in light of its hepatotoxic effects.

Is Antabuse bad for the liver?

This drug may infrequently cause serious (rarely fatal) liver disease. If you notice any of the following unlikely but very serious side effects, tell your doctor immediately: persistent nausea/vomiting, severe stomach/abdominal pain, dark urine, yellowing eyes/skin.

What are the side effects of naltrexone?

The reported side effects include:

  • sleep problems.
  • tiredness.
  • anxiety.
  • headache.
  • joint and muscle pains.
  • abdominal pain and cramps.
  • nausea.
  • vomiting.


Is Campral the same as Antabuse?

Campral (acamprosate) reduces your craving for alcohol, but it works better if you’re also in a support group. Treats alcoholism. While Antabuse (disulfiram) is a good way to help stop alcoholism, it works best if you’re also seeing a therapist.

Is Campral the same as naltrexone?

Campral (acamprosate calcium) and Revia (naltrexone) are used to treat alcohol addiction. Campral is used as part of a complete treatment program that includes both counseling and psychological support.

What does Antabuse feel like?

chest pain, shortness of breath (even with mild exertion); fast or pounding heartbeats or fluttering in your chest; confusion, weakness, spinning sensation, feeling unsteady; or. a light-headed feeling, like you might pass out.

Is disulfiram being discontinued?

Teva discontinued disulfiram tablets in late-2020.

Is there a long acting Antabuse?

For decades, medications available to assist with treatment have been limited to the use of Antabuse, the brand name for Disulfiram beginning in 1951. It was not until 1994 that the use of Vivitrol, a long-acting form of Naltrexone, was approved by the FDA in the treatment of alcohol abuse.

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How long can you use Antabuse?

However, people who weigh less than 110 pounds should wait longer, because body weight can determine how quickly one’s body can rid itself of alcohol. Due to its slow rate of elimination, Antabuse can remain effective in the body for up to 2 weeks after it is used.

Is Naltrexone a disulfiram?

Naltrexone and disulfiram are medications currently approved for treating alcohol dependence. These two medications have different mechanisms of action in the body. In combination they might be effective in treating individuals dually diagnosed with cocaine and alcohol dependence.

What drugs interact with Antabuse?

Some products that may interact with this drug are: alcohol-containing products (such as cough and cold syrups, aftershave), amitriptyline, benznidazole, “blood thinners” (such as warfarin), certain medications for seizures (including hydantoins such as phenytoin/fosphenytoin), isoniazid, metronidazole, theophylline, …

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